Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
Tahoe City, California
There are fundamental aspects of metabolic homeostasis that are regulated
differently in males and females, and influence both the development of diabetes
and obesity and the response to pharmacological intervention. Still, most
preclinical researchers avoid studying female rodents due to the added
complexity of research plans. The consequence is the generation of data that
risks being relevant to only half of the population. This is a timely moment to
study sex differences in diseases as NIH leadership has asked scientists to
consider sex as a biological variable in preclinical research, to ensure that
women get the same benefit of medical research as men. The goal of this meeting
is to fill a need in the scientific community by connecting interdisciplinary
groups of scientists who normally would not have an opportunity to interact.
This group includes investigators studying sex differences, the role of sex
hormones, the systems biology of sex and the genetic contribution of sex
chromosomes to metabolic homeostasis and diseases. Leaders of the pharmaceutical
industry will present their views on sex-specific drug discovery. The meeting is
expected to generate new knowledge and ideas on the importance of gender biology
and medicine from a molecular standpoint to the population level, and to provide
the methods to study them. It is intended to be a catalyst of a process that
will lead to gender-specific treatments of metabolic diseases.
No meeting documents found.
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