Laboratory Smithies
Experiment The editing mutation, Polg(D257A), in mitochondrial DNA polymerase improves diabetes in Akita male mice by suppressing appetite.
Caption Electron micrograph of Polg Akita proximal tubular cell [Consortial]
Strain C57BL6-Ins2-Polg
Animal ID 0603-05
Animal Age 270 day(s) post-natal (d)
Anatomical Site kidney (External Reference)
External Sample ID
Tissue Collection Date Not Specified
Slide Preparation Date Not Specified
Image Acquisition Date Not Specified
Staining Protocol aldehyde fuchsin
Available? Unavailable
Block ID Not Specified
Block Type Not Specified
Sectioning Investigator Not Specified
Magnification Level 2500 X
Gross Description EM Kidney section
Microscopic Description Electron micrograph Polg-Akita proximal tubular cells with mitochondria and
lamellated inclusions in the cytoplasm


AssayAgeMeasured ValueMissing DataComments
 ACR 270urine albumin/urine creatinine ratio 10.939  
 Kid:BW 270total kidney:body weight ratio 0.0159  
 plasma glucose 270glucose, plasma 606.161  
 total ualb 270total albumin excretion 28.014  
 ucreat 270creatinine, urine (Exocell Picric Acid method) 8.83064  
 glucose, urine 270glucose, urine 73.25  
 W rodent 270body mass 25.3  
 water intake 270water intake 41.69