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Pilot & Feasibility
Autophagy as a Common Pathway in Diseases
Autophagy is a carefully choreographed cellular response to stress and
environmental changes. The cell creates specific structures to facilitate
targeted degradation of components in lysosomes, thereby recycling materials and
adjusting cellular contents to suit the new environmental conditions. In recent
years, researchers have implicated disruptions of autophagy in numerous diseases
within the National Institute of Diabetes and Digestive and Kidney Diseases
(NIDDK) mission. These include cystinosis, the systemic amyloidoses, tuberous
sclerosis, acute tubule necrosis, and ciliopathies. The purpose of this
conference is to bring together autophagy researchers and those working on
NIDDK-relevant disease biology to explore potential common mechanisms and to
discuss potential therapeutic development strategies. If successful, this
meeting will promote new collaborations and avenues of investigation that
identify novel diagnostic tools and new interventions and improve clinical
outcomes for diseases relevant to the NIDDK’s mission.
No meeting documents found.
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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