C57BL/6J-Tg(SLC2A4)

The mice were made from an 11.5 kb segment of the human GLUT4 gene containing 5.4 kb 5' untranslated segment and complete coding sequence (as well as intronic sequence) through exon 10. It encodes a complete GLUT4 protein. The mice are on a C57Bl/6 background. Original article is: Olson AL, Liu ML, Moye-Rowley WS, Buse JB, Bell GI, Pessin JE. Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice. J Biol Chem. 1993 May 5;268(13):9839-46.


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