B10.D2-Hc0 H2d H2-T18c/oSnJ

This strain carries the Hc0 allele from DBA/2J, making them serum C5 deficient. Mice have increased susceptibility to certain pathogens and impaired chemotactic responses of neutrophils. Allograft rejection is prolonged. This congenic strain has been used for numerous immunological studies.


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