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We need your help identifying important research questions in complications research. DiaComp supports an interactive web-based dialogue that allows users to submit ideas, vote on existing ideas, or add comments. The results will help us identify future research opportunities. Click Here

Investigator Highlights

NEW! Novel Roles of Mitochondria in Health and Disease

This joint NIDDK/NHLBI workshop will address novel roles for mitochondria in diseases like diabetic complications.

Dates: May 19th - 20th, 2016

Welcome to DiaComp

The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to provide an environment that will foster communication and collaboration between investigator communities involved in complications research.

Toward this goal, DiaComp will:
  1. sponsor annual meetings in complications-relevant scientific areas;
  2. solicit and fund pilot projects in high impact areas of complications research;
  3. support a website to serve the diabetic complications community.


Genotype-Tissue Expression Project Biospecimens Access Policy
The Genotype-Tissue Expression Project (GTEx) Biospecimens Access Policy is now live. The policy and related forms can be found on the GTEx Portal . This mechanism has been put in place to allow access to tissues in the GTEx biobank. Requests can be made either through a "Short" or "Full" Sample Availability/Access Request, depending on the size and scope of the project and whether grant funding for the work is already in place, among other factors. If you have any questions or comments, please e-mail nhgrigtex@mail.nih.gov. NOTE – About one-third of the donors to GTEx had diabetes. A thorough medical history is obtained at the time of donation. Several tissue types of interest to diabetes complications research are available.
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Ossabaw Miniature Swine
The Comparative Medicine Program, which is a joint program of Purdue University and Indiana University School of Medicine represents tremendous interdisciplinary synergy and inter-institutional collaboration. Scientists at these universities have established the only research and large-scale breeding colony of Ossabaw swine in the world that is certified to have a gene mutation, the metabolic syndrome, and heart disease. The striking similarities between swine and human biochemistry, physiology, and pathophysiology provide outstanding opportunities for research in translational medicine.
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Knockout Mouse Project Repository (KOMP)
The KOMP Repository (www.komp.org) is the official archive and distribution center for the Knockout Mouse Project (KOMP), a major 5-year trans-NIH initiative designed to generate null alleles in C57BL/6 embryonic stem (ES) cells for most genes not already available as knockout mice. Nearly 8500 genes are targeted for deletion, most in a conditional-ready format, by mutagenesis teams at "CSD" (Childrens Hospital of Oakland Research Institute, The Sanger Institute, and UC Davis) and at Regeneron, Inc. At the KOMP Repository at UC Davis and CHORI, you can obtain targeting vectors, ES cells, mice, and germplasm, as well as microinjection, genotyping, cryopreservation, breeding, and other services quickly and at reasonable cost to help you with your research project.
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