Sign-up for our newsletter
MAIN
Event Calendar
Awardee Reports
ABOUT DIACOMP
Citing DiaComp
Contact
Committees
Institutions
Awardee Reports
Publications
Bioinformatics
RESOURCES
Protocols & Methods
Reagents & Resources
Mouse Diet
Breeding Schemes
Validation Criteria
IMPC / KOMP Data
Publications
Bioinformatics
CONTACT
PARTICIPANT AREA
Login
▹
Home
Datasets
Welcome to the Datasets page!
We are currently testing this feature and welcome your input.
Here you can query phenotype data by strain, investigator, experiment, experimental condition, and assay. You can filter by sex for selected strains. For selected assays and conditions, you can specify bounded or unbounded ranges of values. DiaComp investigators and their lab members can save criteria for later review.
Click
Add Group
to start new criteria group (indicated by =======OR======== in the display). When you specify more than one group of criteria, you are searching for data that matches all the criteria in group 1 OR all the criteria in group 2, and so on for each group. Within a group, criteria from the same category are ORed together (for example, including Strains 129.A and C57BL6 in the same group will find data for both strains).
NOTE: The selection lists for strains, assays, and experiments show those items that have associated data,
some of which may not be publicly available
. Public users may not not get any results even with minimally restrictive criteria.
Select an existing dataset
[None Selected]
McIndoe: Baseline Phenotyping
McIndoe: Cardiovascular Phenotyping
McIndoe: Nephropathy Phenotyping
McIndoe: Neuropathy Phenotyping
DATASET CRITERIA
Animal age units
day(s) post-natal
week(s) post-natal
month(s) post-natal
year(s) post-natal
Include
Exclude
Strain
Investigator
Experiment
Assay
Condition
(ALRFVB)F1-(Cg)-Tg(Ins2-CALM1)26Ove Tg(Cryaa-TAg)1Ove/PneJ)
(ALRFVB)F1<+/+>
(C57BL/6J X DBA/2J)F2
(NONFVB)F1-(Cg)-Tg(Ins2-CALM1)26Ove Tg(Cryaa-TAg)1Ove/PneJ
(NONFVB)F1<+/+>
(PWKFVB)F1-(Cg)-Tg(Ins2-CALM1)26Ove Tg(Cryaa-TAg)1Ove/PneJ)
(PWKFVB)F1<+/+>
129(B6)-Nos3<tm1.1Rhrs>/J
129B6F1.Cg-Ins2<Akita/+>
129B6F1.Cg-Ins2<Akita/+> Nos3<tm1Unc/+>/J
129B6F1.Cg-Ins2<Akita/+> Nos3<tm1Unc>/J
129B6F1.Cg-Ins2<Akita> Nos3<tm1Unc/+>/J
129B6F1.Cg-Ins2<Akita> Nos3<tm1Unc>/J
129B6F1.Cg-Nos3<tm1Unc>/J
129S6.B6-Ins2<Akita>/CofJ
129S6.Cg-Nos3<tm1Unc> Ins2<+/+>/J
129S6.Cg-Nos3<tm1Unc> Ins2<Akita>/J
129S6/SvEvTac
129S6-Gt(ROSA)26Sor<tm1(Jak2)Bro/+>
129S6-Gt(ROSA)26Sor<tm1(Jak2)Bro/+> Tg(Nphs2-Cre)
129S6-Ins2<Akita/+> Gt(ROSA)26Sor<tm1(Jak2)Bro/+> Tg(Nphs2-Cre)
129S6-Ins2<Akita/+> Gt(ROSA)26Sor<tm1(Jak2)Bro>
B6.129-Adipoq<tm1Chan>/J
B6.129P2-Apoe<tm1Unc>/J
B6.129P2-Apoe<tm1Unc>-129S6/SvEvTac Lias <tm1Mae>/lias+
B6.129P2-Apoe<tm2(APOE*3)Mae>-Ldlr<tm1Her>
B6.129P2-Apoe<tm3(APOE*4)Mae>-Ldlr<tm1Her>
B6.129P2-Nos3<tm1Unc>
B6.129S7-Bdkrb2<tm1Jfh>/JSmi
B6.129S7-Ldlr<tm1Her>/J
B6.Cg-Ins2<Akita> Ldlr<tm1Her>/J
B6.Cg-Nr1h4tm1Gonz/J
B6.Cg-Sod2<+/+> Tg(Jag2-CreERT2(ki))<+/+>
B6.Cg-Sod2<+/+> Tg(Jag2-CreERT2(ki))<Cre/+>
B6.Cg-Sod2<lox/+> Tg(Jag2-CreERT2(ki))<Cre/+>
B6.Cg-Sod2<lox/lox> Tg(Jag2-CreERT2(ki))<+/+>
B6.Cg-Sod2<lox/lox> Tg(Jag2-CreERT2(ki))<Cre/+>
BALB/cJ
BALB/C-Tbxa2r<tm1Cof>
BKS.Cg-Dock7<m> +/+ Lepr<db>
BKS.Cg-Lepr<db> Nos3<tm1Unc>/RhrsJ
BTBR.V(B6)<+/?>/WiscJ
BTBR.V(B6)-Lep<ob>/WiscJ
C57BL/6
C57BL/6-Bdkrb1/Bdkrb2<tm2Mki>/J
C57BL/6-Ins2<Akita> Bdkrb1/Bdkrb2<tm2Mki>/J
C57BL/6-Ins2<Akita>Apoe<tm1Unc>/J
C57BL/6-Ins2<Akita>Nos3<tm1Unc>/J
C57BL/6J
C57BL/6J-Dcn<+/->
C57BL/6J-Dcn<tm1Bot>
C57BL/6J-Ins2<Akita/+> Bdkrb2<tm1Jfh> /JSmi
C57BL/6J-Ins2<Akita>
C57BL/6J-Tbxa2r<tm1Cof>
C57BL6-Ins2<Akita/+>
C57BL6-Ins2<Akita/+>-Polg<D257A/+>
C57BL6-Ins2<Akita/+>-Polg<D257A-/->
D2.B6-Ins2<Akita>/MatbJ
D2.Cg-Ins2 <Akita> Nr1h4<tm1Gonz>/J
D2.Cg-Nr1h4<tm1Gonz>/J
DBA/1LacJ
DBA/1lacJ-Ptges<tm1coff>
DBA/2J
DBA/2J-Ins2<Akita>
FVB(Cg)<+/+>/PneJ
FVB(Cg)-Tg(Ins2-CALM1)26Ove Tg(Cryaa-TAg)1Ove/PneJ
FVB.B6-Ins2<Akita>/MlnJ
FVB.BKS(D)-+/?/ChuaJ
FVB.BKS(D)-Lepr <db>/ChuaJ
FVB.Cg-Ins2<Akita> Nr1h4<tm1Gonz>/J
FVB.Cg-Nr1h4<tm1Gonz>/J
FVB/NJ
FVB-Ins2<Akita>
KK/Ta-Ins2<Akita>
NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl> Lepr<db-5J/+>/Sz
NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl> Lepr<db-5J>/Sz
NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/Sz
SWR/J
Sex
M+F
M
F
Center:
Core:
[Brosius] Podocyte-Specific JAK2 Overexpression Augments Diabetic Nephropathy (DN) in 129S6 Mice
[Coffman] STZ-induced DM in male C57BL/6J and male BALB/cJ mice where the Tbxa2r gene has been disrupted
[Coffman] STZ-induced DM in male DBA/1lacJ mice where the mPGES1 gene has been disrupted
[Daneshgari] Phenotyping of SOD2/Cre Mice
[Davis] Liver Expression in BXD F2 db/db mice
[Feldman] BKS db/db 12 and 24 Week Phenotyping Experiement
[Feldman] BKS db/db 12 and 24 Week Phenotyping Experiement
[Feldman] Btbr ob/ob Neuropathy phentotyping
[Feldman] Btbr ob/ob Neuropathy phentotyping
[Feldman] C57bl STZ dosage
[Feldman] C57bl STZ dosage
[Feldman] C57bl/6 high Fat Diet
[Feldman] C57bl/6 high Fat Diet
[Feldman] C57Bl/6 High Fat Diet Experiment 3
[Feldman] C57Bl/6 High Fat Diet Experiment 3
[Feldman] DBA/2J Fenofibrate Diet study
[Feldman] DBA/2J Fenofibrate Diet study
[Feldman] Netrin treated Swiss Webster Mice
[Feldman] Netrin treated Swiss Webster Mice
[Hsueh] Liver Expression in BXD F2 db/db mice
[Kretzler] Transcriptome profile of diabetic glomeruli in BKS mice homozygous for the db mutation (db/db)
[Kretzler] Transcriptome profile of STZ induced diabetic glomeruli in DBA/2J mice
[Kretzler] Transcriptomic profile of diabetic glomeruli in BKS.Cg-m Leprdb/Nos3tm1Unc/RhrsJ
[Leiter] Baseline Metabolic Phenotyping for DCC Mouse Strains
[Leiter] Cardiovascular and Cardiomyopathy Phenotyping for DCC Mouse Strains
[Leiter] Nephropathy Phenotyping for DCC Mouse Strains
[Leiter] Neuropathy Phenotyping for DCC Mouse Strains
[Levi] Characterization of diabetic nephropathy in FXR knockout mice on C57BL/6J background
[Levi] Characterization of diabetic nephropathy in FXR knockout mice on DBA/2J background
[Levi] Characterization of diabetic nephropathy in FXR knockout mice on FVB/NJ background
[Maeda] ApoE_129_sun_sort_3
[Maeda] Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice
[Maeda] Human apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor
[Maeda] STZ-induced DM in male C57BL/6J and male BALB/cJ mice where the Tbxa2r gene has been disrupted
[Maeda] STZ-induced DM in male DBA/1lacJ mice where the mPGES1 gene has been disrupted
[Sharma] Adiponecitn KO mice characterization
[Sharma] Adiponecitn KO mice characterization
[Sharma] Maggie Diamond-Stanic
[Sharma] Maggie Diamond-Stanic
[Shultz] NSG lepr blood glucose measurements 27-500 days
[Smithies] A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy
[Smithies] Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet
[Smithies] Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
[Smithies] The editing mutation, Polg(D257A), in mitochondrial DNA polymerase improves diabetes in Akita male mice by suppressing appetite.
[Takahashi] KK/Ta-Ins2-Akita Phenotyping
[Takahashi] KK/Ta-Ins2-Akita Phenotyping
[Takahashi] STZ-induced diabetic eNOS Knockout Phenotyping
[Takahashi] STZ-induced diabetic eNOS Knockout Phenotyping
[Weil] Evaluation of diabetic glomerular pathology in a native american population
McIndoe, Richard
Sharma, Amol
Age
albumin to creatinine ratio
aortic sinus (cross section) lesion area
Arteriolar Hyalinosis
average aortic leaflet A lesion
average aortic leaflet B lesion
average aortic leaflet C lesion
average aortic lesion area
Bladder weight
Bladder weight/body weight
blood pressure: diastole
blood pressure: systole
body length A/N (rodent)
body mass
body surface area
body weight (human)
bone area
bone mineral content
bone mineral density
brain weight (rodent)
cholesterol
cholesterol, HDL (UC)
cholesterol, total
creatinine, blood
creatinine, serum
creatinine, urine (Exocell Picric Acid method)
creatinine, urine (spot)
EKG-Beginning to end of QRS complex
EKG-Interval between R-waves
EKG-Interval between the peak of P-wave to Q-wave
EKG-Interval between the peak of P-wave to R-wave
EKG-Interval between the peak of Q-wave to end of T-wave
EKG-Interval between the peak of S-wave to end of T-wave
EKG-Rate-corrected QT
endothelial cell density
endothelial/mesangial cell number
energy intake (24 hr)
fasting glucose
fat body mass
fat tissue, retroperitoneal
fat tissue, subcutaneous
fenestrated endothelium
fenestrated endothelium opposite denuded basement membrane
filtration slit frequency
foot process width
GFR creatinine clearance (HPLC)
GFR inulin clearance (FITC-inulin IV bolus injection)
glomerular basement membrane - denuded
glomerular basement membrane thickness
glomerular filtration rate
glomerular volume
glomeruli globally sclerosed
glomeruli number
glucose, basal
glucose, blood
glucose, plasma
glucose, urine
glutamine dehydrogenase
glycosylated hemoglobin
HbA1c
heart rate
heart:body weight ratio
Height (human)
hematocrit
insulin, blood
insulin, plasma
intraepidermal nerve fibers
intraperitoneal glucose tolerance test: 000min (baseline)
intraperitoneal glucose tolerance test: 005min post-injection
intraperitoneal glucose tolerance test: 015min post-injection
intraperitoneal glucose tolerance test: 030min post-injection
intraperitoneal glucose tolerance test: 060min post-injection
intraperitoneal glucose tolerance test: 120min post-injection
Langerhans cells
lean body mass
left kidney weight (mouse)
leptin
liver mass
mean axonal diameter
Mean fractional interstitial area
Mean fractional mesangial area
Mean surface area
mean surface area per glomerulus
mesangial cell density
mesangial index
Mesangial Sclerosis
myelinated fiber number
NEFA
non-esterified free fatty acids
Pancreatic Insulin Content
percent body fat (rodent)
plantar hind paw analgesia test
plasma triglycerides
podocyte density
podocyte number
pulse
right kidney weight (mouse)
sciatic motor conduction velocity
spleen weight
spleen:body weight ratio
sub-epidermal nerve plexi
sural nerve conduction velocity
tail flick analgesia test
total albumin excretion
total body weight
total creatinine excretion
total kidney weight (mouse)
total kidney:body weight ratio
total length of epidermal:dermal border
triglycerides
Tubulo-interstitial fibrosis
unesterified cholesterol
urea nitrogen, blood
urine albumin (Exocell Albulwell M ELISA)
urine albumin (spot)
urine albumin/urine creatinine ratio
urine albumin/urine creatinine ratio (spot)
urine output
water intake
with values from
>
>=
Please enter a numeric value.
to
<
<=
Please enter a numeric value.
age at start of diet (week)
date of biopsy (date)
date of diagnosis (date)
date of phenotyping (date)
Diabetes Phenotype
duration of treatment (days)
duration of treatment (weeks) (week)
Experimental Group
IP STZ dosage plan
IP STZ Dose (mg/kg) (milligrams per kilogram)
Mouse Diet
OHT Injection
STZ Injection
time since baseline (week)
time since Type 1 Diabetes onset (week)
Total Time on Diet (wk) (week)
Treatment
Treatment Protocol
=
<>
>
>=
<
<=
with values from
>
>=
Please enter a numeric value.
to
<
<=
Please enter a numeric value.
Welcome to the DiaComp Login / Account Request Page.
Email Address:
Password:
Note: Passwords are case-sensitive.
Please save my Email Address on this machine.
Not a member?
If you are a funded DiaComp investigator, a member of an investigator's lab,
or an External Scientific Panel member to the consortium, please
request an account.
Forgot your password?
Enter your Email Address and
click here.
ERROR!
There was a problem with the page:
User Info
User Confirm
Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
Citation text and image have been copied to your clipboard. You may now paste them into your document. Thank you!