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Animal Data

Investigator	Ed Leiter
Animal ID	7562M223
Species	M. musculus
Strain	D2.B6-Ins2Akita/MatbJ
Sex	Male
DOB	4/7/2010
DOD	10/12/2010

Experiments
Name Investigator Baseline Metabolic Phenotyping for DCC Mouse Strains Leiter

Phenotype Assays

Name Abbreviation Units urine albumin (Exocell Albulwell M ELISA) ualb µg/ml creatinine, urine (Exocell Picric Acid method) ucreat mg/dL cholesterol, total TC mg/dL cholesterol, HDL (UC) HDL-UC mg/dL blood pressure: systole sBP mmHg body mass W rodent g urea nitrogen, blood BUN mg/dL hematocrit Hct urine albumin/urine creatinine ratio ACR µg/mg fractional mesangial matrix volume/glomerulus Vv(MM/glom) glomerular volume Glom Vol µm³ total mesangial matrix volume Tot Mes Matrix Vol µm³ left kidney weight (mouse) L Kid Wt g right kidney weight (mouse) R Kid Wt g total albumin excretion total ualb µg insulin, plasma pg/ml spleen weight Spleen Wt g spleen:body weight ratio Spleen:BW aortic sinus (cross section) lesion area μm heart rate HR bpm percent body fat (rodent) %BF (rodent) % body length A/N (rodent) A/N (rodent) cm urine output urine output ml triglycerides TG mg/dL fat body mass g lean body mass g pulse bpm non-esterified free fatty acids NEFA µmol/l glucose, plasma plasma glucose mg/dL leptin ng/dl bone mineral density BMD g/cm² bone mineral content BMC g bone area bone area cm² brain weight (rodent) brain weight (rodent g glutamine dehydrogenase GLDH U/L EKG-Interval between the peak of P-wave to R-wave EKG-PR msec EKG-Interval between R-waves EKG-RR msec EKG-Interval between the peak of P-wave to Q-wave EKG-PQ msec EKG-Interval between the peak of Q-wave to end of T-wave EKG-QT msec EKG-Rate-corrected QT EKG-QTc msec EKG-Beginning to end of QRS complex EKG-QRS msec EKG-Interval between the peak of S-wave to end of T-wave EKG-ST msec Arteriolar Hyalinosis Arteriolar Hyalinosis Mesangial Sclerosis Mesangial Sclerosis urine albumin (spot) ualb-spot µg/ml creatinine, urine (spot) ucreatinine-spot mg/dL urine albumin/urine creatinine ratio (spot) ACR-spot µg/mg Pancreatic Insulin Content PIC ng/µg

Models
Model Type Strain All Complications D2.B6-Ins2Akita/MatbJ