Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption FVB-FXRnull non-diabetic control liver showing widespread ceroid-like pigment [Consortial]
Strain FVB.Cg-Nr1h4/J
Animal ID 7092M414
Animal Age 26 week(s) post-natal (w)
Anatomical Site liver (External Reference)
External Sample ID
Tissue Collection Date 5/13/2010
Slide Preparation Date Not Specified
Image Acquisition Date 5/27/2010
Staining Protocol Periodic acid Schiff (PAS)
Available? Unavailable
Block ID 10-680
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 100 X
Gross Description PAS stain of a moderately steatotic liver
Microscopic Description Multiple foci of a PAS-positive ceroid-like pigment are seen in bile canniculi.
Absence of stainability with Fouchet's stain (not shown) indicates that the
pigment is not bile. Note that leukocytes, particularly macrophages, are
associated with some of the pigment accumulations.