Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption Hyperplastic hypertrophied pancreatic islets from 26-wk-old FVB-Leprdb/db female [Consortial]
Strain FVB.BKS(D)-Lepr /ChuaJ
Animal ID 6654F12
Animal Age 26 week(s) post-natal (w)
Anatomical Site pancreas (External Reference)
External Sample ID
Tissue Collection Date Not Specified
Slide Preparation Date Not Specified
Image Acquisition Date Not Specified
Staining Protocol aldehyde fuchsin
Available? Unavailable
Block ID Not Specified
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 100 X
Gross Description obese FVB-db/db female, body weight = 56.5g; plasma glucose = 138 mg/dl at 24 wk
of age
Microscopic Description high magnification view of hyperplastic and hypertrophied pancreatic islets.
Aldehyde fuchsin staining for beta cell granulation shows some beta cells are
partially degranulated. Strongest granulation is around the numerous intra-islet
capillaries.