Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption FVB-FXRnull non-diabetic female control liver showing ceroid-like pigment accumulation [Consortial]
Strain FVB.Cg-Nr1h4/J
Animal ID 7092F402
Animal Age 26 week(s) post-natal (w)
Anatomical Site liver (External Reference)
External Sample ID 10-662
Tissue Collection Date 5/11/2010
Slide Preparation Date Not Specified
Image Acquisition Date 5/27/2010
Staining Protocol Periodic acid Schiff (PAS)
Available? Unavailable
Block ID Not Specified
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 400 X
Gross Description Fatty liver with pigment accumulation
Microscopic Description Higher magnification showing macrovesicular hepatosteatosis and PAS-positive
ceroid-like pigment in bile canaliculi. The pigment is negative by Fouchet's
stain so is not a bile-derived pigment.