Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption Hyperplastic hypertrophied pancreatic islets from 26-wk-old FVB-Lepr db/db female [Consortial]
Strain FVB.BKS(D)-Lepr /ChuaJ
Animal ID 6654F21
Animal Age 26 week(s) post-natal (w)
Anatomical Site pancreas (External Reference)
External Sample ID
Tissue Collection Date Not Specified
Slide Preparation Date Not Specified
Image Acquisition Date Not Specified
Staining Protocol aldehyde fuchsin
Available? Unavailable
Block ID Not Specified
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 20 X
Gross Description obese FVB-db/db female; 24 wk body weight = 54.9g; plasma glucose = 304 mg/dl
Microscopic Description Extensive hyperplasia of partially aldeyde fuchsin-degranulated islets. The
larger islets contain large blood-filled sinuses. Note the focal replacement of
exocrine cells by fat.