Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption FVB-+/Akita female [Consortial]
Strain FVB.B6-Ins2/MlnJ
Animal ID 6867F15
Animal Age 26 week(s) post-natal (w)
Anatomical Site pancreas (External Reference)
External Sample ID
Tissue Collection Date 9/11/2008
Slide Preparation Date Not Specified
Image Acquisition Date 1/23/2009
Staining Protocol aldehyde fuchsin
Available? Unavailable
Block ID Not Specified
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 200 X
Gross Description moderately hyperglycemic +/Akita female
Body weight =22g; plasma glucose=301 mg/dl at 24 wk
Microscopic Description islets exhibit disturbed architecture and contain variably degranulated beta
cell. However, the fact that granulated beta cells (blue stain) are present in
reasonable numbers markedly distinguishes the Akita females from the Akita
males. Beta cells in the latter are nearly completely degranulated, and islets
are less prevalent.