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Jennifer Pluznick
Personal Information
Title
Associate Professor
Expertise
Nephropathy
Institution
Johns Hopkins University
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Defining the Influence of the Gut Microbiome on Diabetic Renal Disease
The intestinal lumen houses a diverse array of commensal bacteria referred to as the gut microbiota, which play a significant role in host health. Although much past work has focused on how the gut microbiota are remodeled or altered in disease, in this proposal we will focus on how the host is altered by the presence of gut microbiota. To accomplish this, we will utilize a murine model of type II diabetic kidney disease and will assay both how the gut microbiota alters diabetic renal disease in males and females, and, how the gut microbiota alters host gene expression in diabetic renal disease.
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Steering Committee
The DiaComp Steering Committee is the governing body of the consortium. The principle function of this committee is to guide the scientific direction of the consortium. This is accomplished by creating various subcommittees necessary to advance the scientific goals and providing guidance to the broader complications research community. Policies for the consortium are developed through consultation with the
External Evaluation Committee
Nephropathy
The DiaComp Nephropathy Committee has the principal function of furthering the mission of the consortium with regard to diabetic kidney disease.
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Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
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