Sign-up for our newsletter
MAIN
Event Calendar
Awardee Reports
ABOUT DIACOMP
Citing DiaComp
Contact
Committees
Institutions
Awardee Reports
Funding Programs
Pilot & Feasibility
Conference Support
Summer Student
Collaborative
External Funding Programs
Publications
Bioinformatics
RESOURCES
Protocols & Methods
Reagents & Resources
Mouse Diet
Breeding Schemes
Validation Criteria
IMPC / KOMP Data
Publications
Bioinformatics
FUNDING PROGRAMS
Pilot & Feasibility
Conference Support
Summer Student
Collaborative
External Funding Programs
CONTACT
PARTICIPANT AREA
Login
Request Account
▹
Publications
Publication
Insulin Signaling in Heart Muscle: - Lessons from Genetically Engineered
Authors
E. Dale Abel
Submitted By
E. Dale Abel on 8/5/2005
Status
Published
Journal
Current hypertension reports
Year
2004
Date Published
12/1/2004
Volume : Pages
6 : 416 - 423
PubMed Reference
15527684
Abstract
The heart is an insulin-responsive organ, and disorders o finsulin action, such
as diabetes and obesity, can have profound effects on cardiac performance.
Insulin signaling influences numerous functions within the heart, such as
netabolic substrate preference, cell size, and the response of the heart to
ischemia and hypertrophy. Because the systemic consequences of altered insulin
action can have significant but indirect effects on the heart, the generation of
mice with altered expression of insulin receptors and key components of the
insulin-signal transduction pathyways in cardiomyocytes have led to interesting
and occasionally suprising new insights into the regulation of cardiac biology
by insulin.
Investigators with authorship
Name
Institution
E. Dale Abel
University of Iowa
Complications
All Complications
Bioinformatics
Bone
Cardiomyopathy
Cardiovascular
Gastro-Intestinal (GI)
Nephropathy
Neuropathy & Neurocognition
Pediatric Endocrinology
Retinopathy
Uropathy
Wound Healing
Welcome to the DiaComp Login / Account Request Page.
Email Address:
Password:
Note: Passwords are case-sensitive.
Please save my Email Address on this machine.
Not a member?
If you are a funded DiaComp investigator, a member of an investigator's lab,
or an external advisor to the consortium, please
request an account.
Forgot your password?
Enter your Email Address and
click here.
ERROR!
There was a problem with the page:
User Info
User Confirm
Safari Browser Detected...
We strive to make the DiaComp site compatable with as many browsers as possible, but some of our third party tools don't work with the Safari browser.
In order to explore this site we highly recommend using the most recent versions of the following browsers:
Internet Explorer
Google Chrome
FireFox
Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:
Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255
Citation text and image have been copied to your clipboard. You may now paste them into your document. Thank you!