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Publication

Tolerating diabetes: an alternative therapeutic approach for diabetic neuropathy.

Authors Calcutt NA Submitted By Nigel Calcutt on 1/30/2013 Status Published Journal ASN neuro Year 2010 Date Published 5/1/2010 Volume : Pages 2 : e00042 PubMed Reference 20842208 Abstract It is becoming apparent that a number of pathogenic mechanisms contribute to diabetic neuropathy, so that therapeutic interventions that target one particular mechanism may have limited success. A recently published preclinical study has adopted an alternative approach by using a novel small molecule to induce heat-shock protein 70. This confers upon neurons, and perhaps other cells of the nervous system, the ability to better tolerate the diverse stresses associated with diabetes rather than intervening in their production.

Investigators with authorship
Name Institution Nigel Calcutt University of California San Diego

No Complications