Adipokines protecting CKD.
Authors Miyamoto S, Sharma K
Submitted By Kumar Sharma on 12/20/2013
Status Published
Journal Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Year 2013
Date Published 11/1/2013
Volume : Pages 28 Suppl 4 : iv15 - iv22
PubMed Reference 24179009
Abstract Increasing incidence of chronic kidney disease (CKD) which leads to end-stage
renal disease (ESRD) is one of the major health issues in the modern world and
requires novel strategies for treatment. Adipose tissue has been recognized to
have endocrine function and secretes a variety of hormones called adipokines.
Several adipokines have been implicated in the pathogenesis of CKD and may have
a strong impact as a risk factor for renal decline. The aim of this review is to
provide an overview of the role of adipokines in the progression of CKD, with
focus on recent experimental and clinical advances.

Investigators with authorship
Kumar SharmaUniversity of California San Diego