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Publication

How to find a prognostic biomarker for progressive diabetic nephropathy.

Authors Brosius FC, Pennathur S Submitted By Submitted Externally on 2/7/2014 Status Published Journal Kidney international Year 2013 Date Published 6/1/2013 Volume : Pages 83 : 996 - 998 PubMed Reference 23728003 Abstract As a prognostic biomarker for progression of diabetic nephropathy, albuminuria fails in terms of sensitivity and specificity. Better urinary or plasma biomarkers are needed that can predict which diabetic patients are at highest risk for progression. Bhensdadia et al. report proteomic investigations that identified urinary haptoglobin as a potential prognostic biomarker for progressive diabetic nephropathy. Although as a single marker urinary haptoglobin adds little to albuminuria, together the two appear to provide better diagnostic accuracy than albuminuria alone.

Investigators with authorship
Name Institution Frank Brosius University of Arizona

Complications
All ComplicationsBioinformatics BoneCardiomyopathy CardiovascularGastro-Intestinal (GI) NephropathyNeuropathy & Neurocognition Pediatric Endocrinology Retinopathy UropathyWound Healing