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Publication

An integrated approach to diabetic retinopathy research.

Authors Gardner TW, Abcouwer SF, Barber AJ, Jackson GR Submitted By Submitted Externally on 4/15/2014 Status Published Journal Archives of ophthalmology Year 2011 Date Published 2/1/2011 Volume : Pages 129 : 230 - 235 PubMed Reference 21320973 Abstract This review discusses the pathophysiology of diabetic retinopathy related to direct effects of loss of insulin receptor action and metabolic dysregulation on the retina. The resulting sensory neuropathy can be diagnosed by structural and functional tests in patients with mild nonproliferative diabetic retinopathy. Research teams can collaborate to integrate ocular and systemic factors that impair vision and to design strategies to maintain retinal function in persons with diabetes mellitus. Evolving concepts may lead to inclusion of tests of retinal function in the detection of diabetic retinopathy and neuroprotective strategies to preserve vision for persons with diabetes.

Investigators with authorship
Name Institution Steven Abcouwer University of Michigan-Ann Arbor Alistair Barber Pennsylvania State University-Penn State College of Medicine

Complications
All ComplicationsBioinformatics BoneCardiomyopathy CardiovascularGastro-Intestinal (GI) NephropathyNeuropathy & Neurocognition Pediatric Endocrinology Retinopathy UropathyWound Healing