Animal models of regression/progression of kidney disease.
Authors Lim BJ, Yang HC, Fogo AB
Submitted By Agnes Fogo on 9/28/2015
Status Published
Journal Drug discovery today. Disease models
Year 2014
Date Published
Volume : Pages 11 : 45 - 51
PubMed Reference 25722733
Abstract Current medical therapies may delay chronic kidney disease progression. However,
increasing experimental evidence indicates remission or even regression can be
achieved. In order to study mechanisms progression vs. regression by different
interventions, appropriate animal models and research design must be
implemented. We review key information of selected models, including etiology,
pathogenesis, procedure, time course and assessment of potential regression.

Investigators with authorship
Agnes FogoVanderbilt University