Efficacy of Gastric Electrical Stimulation for Gastroparesis: US/European
Authors Burlen J, Runnels M, Mehta M, Andersson S, Ducrotte P, Gourcerol G, Lindberg G,
Fullarton G, Abrahamsson H, Al-Juburi A, Lahr C, Rashed H, Abell T
Submitted By Thomas Abell on 11/5/2018
Status Published
Journal Gastroenterology research
Year 2018
Date Published 10/1/2018
Volume : Pages 11 : 349 - 354
PubMed Reference 30344806
Abstract Gastric electrical stimulation (GES) is used in both the US and Europe, but
little research has investigated the demographics of gastroparesis patients
receiving GES by geographic location., We compared data from 380 patients, 296
female and 84 males, mean age 42 years, 246 idiopathic (ID), 107 diabetic (DM),
and 27 post-surgical (PS). The statistical significance was calculated by
Chi-square test and a P-value obtained for ID, DM, and PS. The statistical
significance was calculated by Fischer exact test and a P-value obtained
comparing male vs. female., European centers had 61 GES patients compared to 319
from the US. In Europe, 100% of patients had gastric emptying test (GET) values
available; in the US, it was 75% of patients. European centers had more DM
patients (59%) than the US (22%), and a smaller proportion of ID patients (25%)
than the US (72%). There was a statistical difference between the causes of
gastroparesis in the patients receiving GES (P-value < 0.00001). There was also
significant difference in the gender of the patients receiving GES, with a
greater proportion of women in the US (P value = 0.0023)., Comparing GES in US
vs. Europe demonstrated significant differences in gastroparesis demographics
and percentage of patients with GET data. After analyzing the previously
discussed results and reviewing recent updates in evidence-based medicine
guidelines, the discrepancy and variance in patient populations in the US and
Europe emphasizes the need for a database that allows better analysis and
treatment of gastroparesis patients worldwide including stimulation therapies.