DiaComp :: Strain

C57BL/6J-Lepr^db Apoe^tm1Unc

Summary

Data Summary

Species	M. musculus
Official Name	C57BL/6J-Lepr^db Apoe^tm1Unc
Common Name	C57BL/6J ^db/db Apoe^-/-
Development Status	Phenotyping ongoing
Creation Method	congenic
Maternal Strain	B6.BKS(D)-Lepr^db/J
Paternal Strain	B6.129P2-Apoe^tm1Unc/J
Background	C57BL/6J

Type	Count
Investigators	1
Genomics - Modifications	2
Models	1

Investigators

Name	Institution
Matthew Breyer	Johnson & Johnson

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Lepr	point mutation - transition	point mutation - transition	Not Specified
Apoe	knockout	knockout	Not Specified

Models

Complication	Strain	Diabetes Type	Status	Investigators
Nephropathy	C57BL/6J-Lepr^db Apoe^tm1Unc	Type II	Phenotyping Ongoing	Breyer, Matthew

Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:

Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255

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