DiaComp :: Strain

B6.129-Gulo^tm1UNC

Summary

Data Summary

Species	M. musculus
Official Name	B6.129-Gulo^tm1UNC
Common Name	B6.129-Gulo^tm1UNC
Development Status	Phenotyping ongoing
Creation Method	knockout
Maternal Strain	C57BL/6J
Paternal Strain	C57BL/6J
Background	C57BL/6J
Phenotype Description	Homozygous mutants are not able to synthesize ascorbic acid. These mice need to be supplemented for survival.

Type	Count
Investigators	1
Genomics - Modifications	1
Child Strains	1
Models	1

Investigators

Name	Institution
Nobuyo Maeda	University of North Carolina

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Gulo	knockout	knockout	Not Specified

Child Strains

Strain	Species	Development Status	Creation Method
C57BL/6J-Apoe^tm1UNC Gulo^tm1UNC [Consortial]		Phenotyping ongoing	knockout

Models

Complication	Strain	Diabetes Type	Status	Investigators
Cardiovascular	B6.129-Gulo^tm1UNC	Type I	Phenotyping Finalization	Maeda, Nobuyo

Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:

Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255

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