DiaComp :: Strain

C57BL/6J-Apoe^tm1UNC Gulo^tm1UNC

Summary

Data Summary

Species	M. musculus
Official Name	C57BL/6J-Apoe^tm1UNC Gulo^tm1UNC
Common Name	vitc/E
Development Status	Phenotyping ongoing
Creation Method	knockout
Paternal Strain	B6.129-Gulo^tm1UNC
Background	C57BL/6J
Phenotype Description	homozygous mutant mice for the gulo gene are not able to produce vitamen c and must be supplemented with ascorbic acid to survive.

Type	Count
Investigators	1
Genomics - Modifications	2
Models	1

Investigators

Name	Institution
Nobuyo Maeda	University of North Carolina

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Apoe	knockout	knockout	Not Specified
GULO	knockout	knockout	Not Specified

Models

Complication	Strain	Diabetes Type	Status	Investigators
Cardiovascular	C57BL/6J-Apoe^tm1UNC Gulo^tm1UNC	Type I	Phenotyping Finalization	Maeda, Nobuyo

Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:

Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255

diacomp_logo

Citation text and image have been copied to your clipboard. You may now paste them into your document. Thank you!