| Description |
Although C57BLKS/J is estimated to have more than 70% of its
genome derived from C57BL/6J, these strains are
phenotypically distinct. Diet-induced atherosclerotic
lesions are much more severe in C57BLKS/J than in C57BL/6J
or many other inbred strains. Compared with a panel of
inbred strains, C57BLKS/J was found to have low total
cholesterol and low HDL cholesterol when fed a normal diet
and high total cholesterol and HDL cholesterol in an
atherogenic diet.
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