Laboratory Leiter
Experiment Baseline Metabolic Phenotyping for DCC Mouse Strains
Caption Kidney lesions in 6 month-old Akita male [Consortial]
Strain D2.B6-Ins2/MatbJ
Animal ID 7562M223
Animal Age 24 week(s) post-natal (w)
Anatomical Site kidney (External Reference)
External Sample ID 10-1485
Tissue Collection Date 10/12/2010
Slide Preparation Date Not Specified
Image Acquisition Date 5/5/2011
Staining Protocol H&E Staining
Available? Unavailable
Block ID 10-1485
Block Type Paraffin
Sectioning Investigator Leiter, Ed
Magnification Level 20 X
Gross Description mouse was necropsied one week earlier than scheduled because it appeared
moribund after first 24 hours in urine collection cage.
Microscopic Description kidney shows extensive mild mesangial matrix expansion; focal proximal tubular
epithelial cell degeneration with droplet formation in lumen.