| | Knockout of insulin receptors in cardiomyocytes attenuates coronary arterial dysfunction induced by pressure overload.Symons JD, Hu P, Yang Y, Wang X, Zhang QJ, Wende AR, Sloan CL, Sena S, Abel ED, Litwin SE American journal of physiology. Heart and circulatory physiology, 2011 (300), H374 - H381 | | | 20971769 | Published |
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| | Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice.Sloan C, Tuinei J, Nemetz K, Frandsen J, Soto J, Wride N, Sempokuya T, Alegria L, Bugger H, Abel ED Diabetes, 2011 (60), 1424 - 1434 | | | 21441440 | Published |
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| | Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.Shimizu I, Minamino T, Toko H, Okada S, Ikeda H, Yasuda N, Tateno K, Moriya J, Yokoyama M, Nojima A, Koh GY, Akazawa H, Shiojima I, Kahn CR, Abel ED, Komuro I The Journal of clinical investigation, 2010 (120), 1506 - 1514 | | | 20407209 | Published |
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| | Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding.Wright JJ, Kim J, Buchanan J, Boudina S, Sena S, Bakirtzi K, Ilkun O, Theobald HA, Cooksey RC, Kandror KV, Abel ED Cardiovascular research, 2009 (82), 351 - 360 | | | 19147655 | Published |
| | Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.Boudina S, Bugger H, Sena S, O'Neill BT, Zaha VG, Ilkun O, Wright JJ, Mazumder PK, Palfreyman E, Tidwell TJ, Theobald H, Khalimonchuk O, Wayment B, Sheng X, Rodnick KJ, Centini R, Chen D, Litwin SE, Weimer BE, Abel ED Circulation, 2009 (119(9)), 1272 - 1283 | | | 19237663 | Published |
| | Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction.Sena S, Hu P, Zhang D, Wang X, Wayment B, Olsen C, Avelar E, Abel ED, Litwin SE. Journal of molecular and cellular cardiology, 2009 (46(6)), 910 - 918 | | | 19249310 | Published |
| | Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.Symons JD, McMillin SL, Riehle C, Tanner J, Palionyte M, Hillas E, Jones D, Cooksey RC, Birnbaum MJ, McClain DA, Zhang QJ, Gale D, Wilson LJ, Abel ED Circulation research, 2009 (104), 1085 - 1094 | | | 19342603 | Published |
| | Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice.Bugger H, Chen D, Riehle C, Soto J, Theobald HA, Hu XX, Ganesan B, Weimer BC, Abel ED Diabetes, 2009 (58(9)), 1986 - 1997 | | | 19542201 | Published |
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| | Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3Bugger H, Boudina S, Hu XX, Tuinei J, Zaha VG, Theobald HA, Yun UJ, McQueen AP, Wayment B, Litwin SE, Abel ED Diabetes, 2008 (57), 2924 - 2932 | | | 18678617 | Published |
| | Recipes for Creating Animal Models of Diabetic Cardiovascular DiseaseWilla Hsueh, E. Dale Abel, Jan L. Breslow, Nobuyo Maeda, Richard C. Davis, Edward A. Fisher, Hayes Dansky, Donald A. McClain, Richard McIndoe, Momtaz K. Wassef, Cristina Rabadan-Diehl, Ira J. Goldberg Circulation research, 2007 (100), 1415 - 1427 | | | 17525381 | Published |
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| | Mitochondrial energetics in the heart in obesity related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteinsSihem Boudina, Sandra Sena, Heather Theobald, Xiaoming Sheng, Jordan J. Wright, Xia Xuan Hu, Salwa Aziz, Josie I. Johnson, Heiko Bugger,Vlad G. Zaha and E. Dale Abel Diabetes, 2007 (56(10)), 2457 - 2466 | | | 17623815 | Published |
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| | Cardiac Hypertrophy Caused by Peroxisome Proliferator Activated Receptor-Gamma Agonist Treatment Occurs Independently of Changes in Myocardial Insulin SignalingSandra Sena, Isaac R. Rasmussen, Adam R. Wende, Alfred P. McQueen, Heather A. Theobald, Nicole Wilde, Renata Oliveira Pereira, Sheldon E. Litwin, Joel P. Berger, E. Dale Abel Endocrinology, 2007 (148(12)), 6047 - 6053 | | | 17823261 | Published |
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| | Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and ObesityJonathan Buchanan, Pradip K. Mazumder, Ping Hu, Gopa Chakrabarti, Matthew W. Roberts, Ui Jeong Yun, Robert C. Cooksey, Sheldon E. Litwin, and E. Dale Abel Endocrinology, 2005 (146), 5341 - 5349 | | | 16141388 | Published |
| | Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary densityAlfred P. McQueen, Dongfang Zhang, Ping Hu, LeAnne Swenson, Ying Yang, Vlad G. Zaha, James L. Hoffman, Ui Jeong Yun, Gopa Chakrabarti, ZhengmingWang, Kurt H. Albertine, E. Dale Abel, Sheldon E. Litwin Journal of molecular and cellular cardiology, 2005 (39), 882 - 892 | | | 16216265 | Published |
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| | Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. The Journal of clinical investigation, 2002 (109), 629 - 639 | | | 11877471 | Published |
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