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Publication

The Link Between Obesity and Albuminuria: Adiponectin and Podocyte Dysfunction

Authors Kumar Sharma Submitted By Kumar Sharma on 3/18/2009 Status Published Journal Kidney international Year 2009 Date Published 7/1/2009 Volume : Pages 76(2) : 145 - 148 PubMed Reference 19404275 Abstract With the recent rise in world wide obesity, obesity-related albuminuria is now being recognized as a critical risk factor for cardiovascular disease. However, there is an urgent need to better understand this association. Recent clinical studies suggest that the adipocyte hormone adiponectin may play a key role in the development of obesity-related albuminuria. Moreover, studies with the adiponectin knockout mouse indicate that adiponectin can regulate podocyte function and thus contribute to the initial development of albuminuria. Future studies to examine adipocyte-renal cell biology are needed to develop preventive and therapeutic strategies for combatting the complications of obesity.

Complications
All Complications Bioinformatics Bone Cardiomyopathy Cardiovascular Gastro-Intestinal (GI) Nephropathy Neuropathy & Neurocognition Pediatric Endocrinology Retinopathy Uropathy Wound Healing

Genes
Symbol Description Adipoq adiponectin, C1Q and collagen domain containing