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| | Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice.Ghosh S, Khazaei M, Moien-Afshari F, Ang LS, Granville DJ, Verchere CB, Dunn SR, McCue P, Mizisin A, Sharma K, Laher I American journal of physiology. Renal physiology, 2009 (296(4)), F700 - F708 | | | 19144689 | Published | |
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| | Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS The Journal of biological chemistry, 2009 (284), 1755 - 1764 | | | 18996837 | Published | |
| | Ca2+-independent alterations in diastolic sarcomere length and relaxation kinetics in a mouse model of lipotoxic diabetic cardiomyopathy.Flagg TP, Cazorla O, Remedi MS, Haim TE, Tones MA, Bahinski A, Numann RE, Kovacs A, Schaffer JE, Nichols CG, Nerbonne JM Circulation research, 2009 (104), 95 - 103 | | | 19023131 | Published | |
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| | Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH Diabetes, 2009 (58(1)), 116 - 124 | | | 18952837 | Published | |
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| | Enhanced Expression of JAK-STAT Pathway Members in Human Diabetic NephropathyCeline C. Berthier, PhD., Hongyu Zhang, M.D., MaryLee Schin, B.S., Anna Henger, PhD, Robert G. Nelson, M.D., PhD, Berne Yee, M.D., Anissa Boucherot, PhD., Christin Carter-Su, PhD., Lawrence S. Argetsinger, PhD., Maria Pia Rastaldi, M.D., Frank C. Brosius, M.D., Matthias Kretzler, M.D Diabetes, 2008 (Epub), 469 - 477 | | | 19017763 | Published | |
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| | Myocyte specific overexpression of myoglobin impairs angiogenesis after hind-limb ischemia.Hazarika S, Angelo M, Li Y, Aldrich AJ, Odronic SI, Yan Z, Stamler JS, Annex BH Arteriosclerosis, thrombosis, and vascular biology, 2008 (28(12)), 2144 - 2150 | | | 18818418 | Published | |
| | Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3Bugger H, Boudina S, Hu XX, Tuinei J, Zaha VG, Theobald HA, Yun UJ, McQueen AP, Wayment B, Litwin SE, Abel ED Diabetes, 2008 (57), 2924 - 2932 | | | 18678617 | Published | |
| | Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.Shi S, Yu L, Chiu C, Sun Y, Chen J, Khitrov G, Merkenschlager M, Holzman LB, Zhang W, Mundel P, Bottinger EP Journal of the American Society of Nephrology : JASN, 2008 (19(11)), 2159 - 2169 | | | 18776119 | Published | |
| | Bladder dysfunction in mice with experimental autoimmune encephalomyelitis.Altuntas CZ, Daneshgari F, Liu G, Fabiyi A, Kavran M, Johnson JM, Gulen MF, Jaini R, Li X, Frenkl TL, Tuohy VK Journal of neuroimmunology, 2008 (203(1)), 58 - 63 | | | 18703233 | Published | |
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| | Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathyHongyu Zhang, Jharna Saha, MaryLee Schin, Jaeman Byun, Matthias Kretzler, Eva L. Feldman, David A. Weild, Subramaniam Pennathur, Frank C. Brosius III American journal of physiology. Renal physiology, 2008 (295(4)), F1071 - F1081 | | | 18667486 | Published | |
| | Single amino acid substitution in aquaporin 11 causes renal failure.Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD Journal of the American Society of Nephrology : JASN, 2008 (19(10)), 1955 - 1964 | | | 18701606 | Published | |
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| | The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.Kappas NC, Zeng G, Chappell JC, Kearney JB, Hazarika S, Kallianos KG, Patterson C, Annex BH, Bautch VL The Journal of cell biology, 2008 (181), 847 - 858 | | | 18504303 | Published | |
| | Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes.Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS Diabetes, 2008 (57(6)), 1674 - 1682 | | | 18346984 | Published | |
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| | Association of insulin sensitivity and glucose tolerance with the c.825C>T variant of the G protein beta-3 subunit gene.Kopf D, Cheng LS, Blandau P, Hsueh W, Raffel LJ, Buchanan TA, Xiang AH, Davis RC, Rotter JI, Lehnert H Journal of diabetes and its complications, 2008 (22), 205 - 209 | | | 18413224 | Published | |
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| | Adiponectin regulates albuminuria and podocyte function in mice.Kumar Sharma, M.D., Satish RamachandraRao, Ph.D., Gang Qiu, M.S., Hitomi Kataoka Usui, M.D., Yanqing Zhu, M.D., Stephen R. Dunn, B.S., Raogo Ouedraogo, Ph.D., Kelly Hough, Peter McCue, M.D., Lawrence Chan, M.D., Bonita Falkner, M.D., Barry J. Goldstein, M.D., Ph.D. The Journal of clinical investigation, 2008 (118), 1645 - 1656 | | | 18431508 | Published | |
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| | Cardiac Hypertrophy Caused by Peroxisome Proliferator Activated Receptor-Gamma Agonist Treatment Occurs Independently of Changes in Myocardial Insulin SignalingSandra Sena, Isaac R. Rasmussen, Adam R. Wende, Alfred P. McQueen, Heather A. Theobald, Nicole Wilde, Renata Oliveira Pereira, Sheldon E. Litwin, Joel P. Berger, E. Dale Abel Endocrinology, 2007 (148(12)), 6047 - 6053 | | | 17823261 | Published | |
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| | Impaired Angiogenesis Following Hind-Limb Ischemia in Type 2 Diabetes Mellitus: Differential Regulation of VEGFR1, R2, and Soluble VEGFR-1Surovi Hazarika, MD, PhD; Ayotunde O Dokun, MD, PhD; Younjun Li, MD; Aleksander S. Popel MS, PhD; Christopher D. Kontos, MD; Brian H. Annex, MD Circulation research, 2007 (101(9)), 948 - 956 | | | 17823371 | Published | |
| | Mitochondrial energetics in the heart in obesity related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteinsSihem Boudina, Sandra Sena, Heather Theobald, Xiaoming Sheng, Jordan J. Wright, Xia Xuan Hu, Salwa Aziz, Josie I. Johnson, Heiko Bugger,Vlad G. Zaha and E. Dale Abel Diabetes, 2007 (56(10)), 2457 - 2466 | | | 17623815 | Published | |
| | Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy.Jiang T, Wang XX, Scherzer P, Wilson P, Tallman J, Takahashi H, Li J, Iwahashi M, Sutherland E, Arend L, Levi M Diabetes, 2007 (56), 2485 - 2493 | | | 17660268 | Published | |
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| | Recipes for Creating Animal Models of Diabetic Cardiovascular DiseaseWilla Hsueh, E. Dale Abel, Jan L. Breslow, Nobuyo Maeda, Richard C. Davis, Edward A. Fisher, Hayes Dansky, Donald A. McClain, Richard McIndoe, Momtaz K. Wassef, Cristina Rabadan-Diehl, Ira J. Goldberg Circulation research, 2007 (100), 1415 - 1427 | | | 17525381 | Published | |
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| | A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.Tchekneva EE, Rinchik EM, Polosukhina D, Davis LS, Kadkina V, Mohamed Y, Dunn SR, Sharma K, Qi Z, Fogo AB, Breyer MD Journal of the American Society of Nephrology : JASN, 2007 (18), 103 - 112 | | | 17151334 | Published | |
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| | Glomerular injury is exacerbated in diabetic integrin alpha1-null mice.Zent R, Yan X, Su Y, Hudson BG, Borza DB, Moeckel GW, Qi Z, Sado Y, Breyer MD, Voziyan P, Pozzi A Kidney international, 2006 (70) | | | 16775606 | Published | |
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| | Temporal differences in bladder dysfunction caused by diabetes, diuresis, and treated diabetes in mice.Daneshgari F, Huang X, Liu G, Bena J, Saffore L, Powell CT American journal of physiology. Regulatory, integrative and comparative physiology, 2006 (290), R1728 - R1735 | | | 16439670 | Published | |
| | Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptorsKakoki M, Kizer CM, Yi X, Takahashi N, Kim H-S, Bagnell CR, Edgell CJS, Maeda N, Jennette JC, Smithies O The Journal of clinical investigation, 2006 (116), 1302 - 1309 | | | 16604193 | Published | |
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| | Accelerated Diabetic Nephropathy in Mice Lacking the Peroxisome Proliferator-Activated Receptor-alphaCheol Whee Park, M.D., Hyeong Wook Kim, M.D., Seung Hyun Ko, M.D., Hyun Wha Chung, M.D., Sun Woo Lim, Ph.D., Chul Woo Yang, M.D., Yoon Sik Chang, M.D., Akira Sugawara, M.D., YouFei Guan, M.D., Matthew D. Breyer Diabetes, 2006 (55), 885 - 893 | | | 16567507 | Published | |
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| | Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and ObesityJonathan Buchanan, Pradip K. Mazumder, Ping Hu, Gopa Chakrabarti, Matthew W. Roberts, Ui Jeong Yun, Robert C. Cooksey, Sheldon E. Litwin, and E. Dale Abel Endocrinology, 2005 (146), 5341 - 5349 | | | 16141388 | Published | |
| | Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary densityAlfred P. McQueen, Dongfang Zhang, Ping Hu, LeAnne Swenson, Ying Yang, Vlad G. Zaha, James L. Hoffman, Ui Jeong Yun, Gopa Chakrabarti, ZhengmingWang, Kurt H. Albertine, E. Dale Abel, Sheldon E. Litwin Journal of molecular and cellular cardiology, 2005 (39), 882 - 892 | | | 16216265 | Published | |
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| | A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background.Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ Genomics, 2005 (86(3)), 259 - 270 | | | 16039824 | Published | |
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| | Mouse Models of Diabetic NephropathyMATTHEW D. BREYER, ERWIN BÖTTINGER, FRANK C. BROSIUS, III, THOMAS M. COFFMAN, RAYMOND C. HARRIS, CHARLES W. HEILIG, AND KUMAR SHARMA (FOR THE AMDCC) Journal of the American Society of Nephrology : JASN, 2005 (16), 27 - 45 | | | 15563560 | Published | |
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| | Molecular Profiling of Diabetic Mouse Kidneys Reveals Novel Genes Linked to Glomerular DiseaseKatalin Susztak, Erwin Böttinger, Akiva Novetsky, Dan Liang, Yanqing Zhu, Emilio Ciccone, Dona Wu, Stephen Dunn, Peter McCue, Kumar Sharma Diabetes, 2004 (53), 784 - 794 | | | 14988265 | Published | |
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| | Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient miceBruemmer D, Collins AR, Noh G, Wang W, Territo M, Arias-Magallona S, Fishbein MC, Blaschke F, Kintscher U, Graf K, Law RE, Hsueh WA The Journal of clinical investigation, 2003 (112), 1318 - 1331 | | Submitted Externally | 14597759 | Published | |
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| | Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. The Journal of clinical investigation, 2002 (109), 629 - 639 | | | 11877471 | Published | |
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