DiaComp :: Strain

B6.129S1-Fyn^tm1Sor

Summary

Data Summary

Species	M. musculus
Official Name	B6.129S1-Fyn^tm1Sor
Common Name	129-Fyn ^-/-
Description	Replacement of a 3kb fragment containing the first coding exon of the gene with a neomycin cassette.
Creation Method	knockout
Background	129S1/SvImJ

Investigators

Name	Institution
Eva Feldman	University of Michigan

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Fyn	knockout	knockout	Not Specified

Strain	Species	Development Status	Creation Method
129-Fyn^tm1Sor Lepr^db [Consortial]		Breeding ongoing	congenic

Complication	Strain	Diabetes Type	Status	Investigators
Nephropathy	B6.129S1-Fyn^tm1Sor	Type I	Phenotyping Ongoing	Brosius, Frank