DiaComp :: Strain

C57BL/6j-Gclc^tm1Neb/+ Lepr^db

Summary

Data Summary

Species	M. musculus
Official Name	C57BL/6j-Gclc^tm1Neb/+ Lepr^db
Common Name	C57BL/6j-Gclc^+/- ^db/db
Development Status	Breeding ongoing
Creation Method	congenic
Maternal Strain	C57BL/6J-Gclc ^tm1Neb/+
Paternal Strain	B6.BKS(D)-Lepr^db/J
Background	C57BL/6J

Type	Count
Investigators	1
Genomics - Modifications	2
Models	2

Investigators

Name	Institution
Frank Brosius	University of Arizona

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Gclc	knockout	wild	Not Specified
Lepr	point mutation - transition	point mutation - transition	Not Specified

Models

Complication	Strain	Diabetes Type	Status	Investigators
Nephropathy	C57BL/6j-Gclc^tm1Neb/+ Lepr^db	Type II	Strain Creation	Brosius, Frank
Neuropathy & Neurocognition	C57BL/6j-Gclc^tm1Neb/+ Lepr^db	Type I	Phenotyping Ongoing	Brosius, Frank

Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:

Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255

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