DiaComp :: Strain

C57BL/6J-Slc2a4^tm1Cha Lepr^db

Summary

Data Summary

Species	M. musculus
Official Name	C57BL/6J-Slc2a4^tm1Cha Lepr^db
Common Name	C57BL/6J-Glut4^-/- ^db/db
Development Status	Breeding ongoing
Creation Method	congenic
Maternal Strain	C57BL/6J-Slc2a4^tm1Cha
Paternal Strain	B6.BKS(D)-Lepr^db/J
Background	C57BL/6J

Type	Count
Investigators	2
Genomics - Modifications	2
Models	1

Investigators

Name	Institution
Erwin Bottinger	Mount Sinai School of Medicine
Frank Brosius	University of Arizona

Genomic Information

Gene	Allele 1	Allele 2	Protocol
Slc2a4	knockout	knockout	Not Specified
Lepr	point mutation - transition	point mutation - transition	Not Specified

Models

Complication	Strain	Diabetes Type	Status	Investigators
Nephropathy	C57BL/6J-Slc2a4^tm1Cha Lepr^db	Type II	Strain Creation	Bottinger, Erwin Brosius, Frank

Please acknowledge all posters, manuscripts or scientific materials that were generated in part or whole using funds from the Diabetic Complications Consortium(DiaComp) using the following text:

Financial support for this work provided by the NIDDK Diabetic Complications Consortium (RRID:SCR_001415, www.diacomp.org), grants DK076169 and DK115255

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