Differential susceptibility to diabetic nephropathy in inbred mice
| Summary |
Data Summary |
| Investigator |
Breyer, Matthew |
| Description |
The susceptibility to diabetic nephropathy is being evaluating in six inbred
mice with STZ induced hyperglycemia including C57BL/6J, DBA/2J, A/J, FVB/NJ,
MRL/MpJ and KK/HlJ. Despite the comparable levels of hyperglycemia, diabetic
DBA/2J and KK/HlJ mice developed more albuminuria (ACR) and severe renal
histomorphological changes.
|
| Status |
In Progress |
| Public Release |
4/11/2005 |
| Data Collected? |
Data will not be collected for this catalog item |
| Species |
M. musculus |
| Animal Age |
Measured In: week(s) post-natal (w) |
|
| Data Analysis |
|
|
|
|
| Animals |
|
| Strain Name | Unknown |
| C57BL/6J | 1 | 37 | 0 |
| A/J | 0 | 43 | 0 |
| DBA/2J | 9 | 55 | 0 |
| FVB/NJ | 0 | 14 | 0 |
| KK/HlJ | 0 | 37 | 0 |
| MRL/MpJ | 0 | 29 | 0 |
|
|
Experimental Factor Values