DiaComp :: Member Profile

Nobuyo Maeda

Personal Information

Title	Professor
Expertise	Cardiovascular
Institution	University of North Carolina
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Data Summary

Type	Count
Grants/SubContracts	1
Progress Reports	5
Presentations	4
Publications	30
Protocols	1
Committees	1

Progress Reports

No funding program application progress reports found.

Annual Reports


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Title	Year	Type
Maeda, Nobuyo (2007)	2007	Annual Report
Maeda, Nobuyo (20080	2008	Annual Report
Maeda, Nobuyo (2009)	2009	Annual Report
Maeda, Nobuyo (2010)	2010	Annual Report
Maeda, Nobuyo (2011)	2011	Annual Report

Publication	Submitted By	PubMed ID	Status
Year: 2019; Items: 1
Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production. Kakoki M, Bahnson EM, Hagaman JR, Siletzky RM, Grant R, Kayashima Y, Li F, Lee EY, Sun MT, Taylor JM, Rice JC, Almeida MF, Bahr BA, Jennette JC, Smithies O, Maeda-Smithies N JCI insight, 2019 (4)	Maeda, Nobuyo	31217360	Published
Year: 2016; Items: 1
Influence of Different Levels of Lipoic Acid Synthase Gene Expression on Diabetic Nephropathy. Xu L, Hiller S, Simington S, Nickeleit V, Maeda N, James LR, Yi X PLoS ONE, 2016 (11)	Yi, Xianwen	27706190	Published
Year: 2014; Items: 2
a-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice. Hiller S, DeKroon R, Xu L, Robinette J, Winnik W, Alzate O, Simington S, Maeda N, Yi X Free radical biology & medicine, 2014 (71), 362 - 367	Yi, Xianwen	24675228	Published
Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability. Perez-Diaz S, Johnson LA, DeKroon RM, Moreno-Navarrete JM, Alzate O, Fernandez-Real JM, Maeda N, Arbones-Mainar JM FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014 (28), 3769 - 3779	Submitted Externally	24812087	Published
Year: 2013; Items: 2
Diabetic atherosclerosis in APOE4 mice: synergy between lipoprotein metabolism and vascular inflammation. Johnson LA, Kim HS, Knudson MJ, Nipp CT, Yi X, Maeda N Journal of lipid research*, 2013 (54), 386 - 396	Maeda, Nobuyo	23204275	Published
Connective tissue growth factor (CTGF) expression modulates response to high glucose. James LR, Le C, Doherty H, Kim HS, Maeda N PLoS ONE, 2013 (8), e70441	Maeda, Nobuyo	23950936	Published
Year: 2012; Items: 5
Reduced expression of lipoic acid synthase accelerates diabetic nephropathy. Yi X, Xu L, Hiller S, Kim HS, Nickeleit V, James LR, Maeda N Journal of the American Society of Nephrology : JASN, 2012 (23), 103 - 111	Maeda, Nobuyo	22021711	Published
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. Li F, Hagaman JR, Kim HS, Maeda N, Jennette JC, Faber JE, Karumanchi SA, Smithies O, Takahashi N Journal of the American Society of Nephrology : JASN, 2012 (23), 652 - 660	Takahashi, Nobuyuki	22282588	Published
Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption. Fox RG, Magness S, Kujoth GC, Prolla TA, Maeda N American journal of physiology. Gastrointestinal and liver physiology, 2012 (302), G914 - G924	Maeda, Nobuyo	22345551	Published
Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-? in apolipoprotein E-Null mice. Pendse AA, Johnson LA, Kim HS, McNair M, Nipp CT, Wilhelm C, Maeda N Arteriosclerosis, thrombosis, and vascular biology, 2012 (32), 1436 - 1444	Maeda, Nobuyo	22539598	Published
Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice. Yi X, Xu L, Hiller S, Kim HS, Maeda N Atherosclerosis, 2012 (223), 137 - 143	Maeda, Nobuyo	22658261	Published
Year: 2011; Items: 6
a-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy. Yi X, Nickeleit V, James LR, Maeda N Journal of diabetes and its complications, 2011 (25), 193 - 201	Maeda, Nobuyo	20801062	Published
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N Proceedings of the National Academy of Sciences of the United States of America, 2011 (108), 2070 - 5	Takahashi, Nobuyuki	21245338	Published
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N Proceedings of the National Academy of Sciences of the United States of America, 2011 (108), 2070 - 2075	Smithies, Oliver	21245338	Published
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N Proceedings of the National Academy of Sciences of the United States of America, 2011 (108), 8779 - 8784	Maeda, Nobuyo	21555558	Published
Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis. Huang ZH, Maeda N, Mazzone T Journal of lipid research, 2011 (52), 1733 - 1741	Submitted Externally	21743035	Published
Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor. Johnson LA, Arbones-Mainar JM, Fox RG, Pendse AA, Altenburg MK, Kim HS, Maeda N Diabetes, 2011 (60), 2285 - 2294	Maeda, Nobuyo	21810592	Published
Year: 2010; Items: 4
Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice. Yi X, Xu L, Kim K, Kim HS, Maeda N Atherosclerosis, 2010 (211), 424 - 430	Maeda, Nobuyo	20347443	Published
Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4. Arbones-Mainar JM, Johnson LA, Altenburg MK, Kim HS, Maeda N The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010 (24), 3809 - 3818	Maeda, Nobuyo	20501792	Published
Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet F . L I , C.-H. WANG, J .-G. WANG, T. THAI , G. BOYSEN, L . XU, A. L . TURNER, A. S . WOLBERG, N. MACKMAN, N. MAEDA and N. TAKAHASHI Journal of thrombosis and haemostasis : JTH, 2010 (8), 2122 - 2132	Smithies, Oliver	20626618	Published
Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction. Pendse AA, Johnson LA, Tsai YS, Maeda N Diabetes, 2010 (59), 2890 - 2897	Maeda, Nobuyo	20724579	Published
Year: 2009; Items: 1
Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury. Yi X, Kim K, Yuan W, Xu L, Kim HS, Homeister JW, Key NS, Maeda N Journal of leukocyte biology, 2009 (85(1)), 146 - 153	Maeda, Nobuyo	18845616	Published
Year: 2008; Items: 1
Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice. Arbones-Mainar JM, Johnson LA, Altenburg MK, Maeda N International journal of obesity (2005), 2008 (32(10)), 1595 - 1605	Maeda, Nobuyo	18725890	Published
Year: 2007; Items: 1
Recipes for Creating Animal Models of Diabetic Cardiovascular Disease Willa Hsueh, E. Dale Abel, Jan L. Breslow, Nobuyo Maeda, Richard C. Davis, Edward A. Fisher, Hayes Dansky, Donald A. McClain, Richard McIndoe, Momtaz K. Wassef, Cristina Rabadan-Diehl, Ira J. Goldberg Circulation research, 2007 (100), 1415 - 1427	Goldberg, Ira	17525381	Published
Year: 2006; Items: 3
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors Kakoki M, Kizer CM, Yi X, Takahashi N, Kim H-S, Bagnell CR, Edgell CJS, Maeda N, Jennette JC, Smithies O The Journal of clinical investigation, 2006 (116), 1302 - 1309	Smithies, Oliver	16604193	Published
A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene. Tsai YS, Pendse A, Moy SS, Mohri I, Perez A, Crawley JN, Suzuki K, Maeda N Mammalian genome : official journal of the International Mammalian Genome Society, 2006 (17(7)), 716 - 722	Maeda, Nobuyo	16845470	Published
alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet. Yi X, Maeda N Diabetes, 2006 (55(8)), 2238 - 2244	Maeda, Nobuyo	16873686	Published
Year: 2005; Items: 2
PPARgamma: a critical determinant of body fat distribution in humans and mice. Tsai YS, Maeda N Trends in cardiovascular medicine, 2005 (15(3)), 81 - 85	Maeda, Nobuyo	16039966	Published
Endogenous production of lipoic acid is essential for mouse development. Yi X, Maeda N Molecular and cellular biology, 2005 (25(18)), 8387 - 8392	Maeda, Nobuyo	16135825	Published
Year: 2004; Items: 1
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. Tsai YS, Kim HJ, Takahashi N, Kim HS, Hagaman JR, Kim JK, Maeda N The Journal of clinical investigation, 2004 (114), 240 - 249	Maeda, Nobuyo	15254591	Published


Drag a column header and drop it here to group by that column

Title	Year	Type
Maeda, Nobuyo (2005)	2005	Presentation
Maeda, Nobuyo (2006)	2006	Presentation
Maeda, Nobuyo (2007)	2007	Presentation
Maeda, Nobuyo (2009)	2009	Presentation

Title	Type	Version	Investigator(s)	Inactive
Breeding Scheme and Selection of Animals for DCC Experiments	Breeding	1	Maeda, Nobuyo Smithies, Oliver Takahashi, Nobuyuki	Active

Name	Description
Cardiovascular	The DiaComp Cardiovascular Committee has the principal function of furthering the mission of the consortium with regard to diabetic cardiomyopathy and macrovascular disease.

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